An operating cost comparison between conventional and home quotidian hemodialysis☆
Section snippets
Methods
Ten daily HD, 12 nocturnal HD, and 22 conventional thrice-weekly HD patients were enrolled in the 18-month study.10 The patient who switched from nocturnal HD to daily HD therapy was considered a nocturnal HD patient for this analysis. Conventional HD patients served as matched controls for quotidian HD patients, and a 12-month retrospective chart review allowed each patient to serve as his or her own control. Because of the small number of patients involved, it was hypothesized that using
Results
Table 1 lists the number of weeks that patients were enrolled in both the study and the retrospective analysis. This study represents approximately 105 patient-years of economic data. Variances between groups were caused by deaths, transplantations, and transfers between HD modalities. Subsequent results show that this study, with its relatively small sample size, was clearly underpowered to detect costing differences of statistical significance.
Discussion
The London Daily/Nocturnal Hemodialysis Study is the most comprehensive comparative analysis of costs associated with home quotidian HD to date. As the data show, annual costs for daily HD are substantially less than those for both nocturnal and conventional HD: approximately Can $67,300, Can $74,400, and Can $72,700 per patient, respectively. Annualized QALY values of 0.84, 0.70, and 0.71 for the 3 groups resulted in total annualized cost per QALY of Can $85,400, Can $120,900, and Can
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The London Daily/Nocturnal Dialysis Study was totally financed by a grant from the Ministry of Health and Long-Term Care of the Province of Ontario, Canada. The publication of this supplement was supported by grants from the Ministry of Health and Fresenius Medical Care of North America.