Workup for Metastatic Retinoblastoma: A Review of 261 Patients
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Cited by (48)
Bone metastasis of retinoblastoma five years after primary treatment
2020, American Journal of Ophthalmology Case ReportsCitation Excerpt :Tumor spread of RB is mostly confined to the ocular bulb or infrequently locally to intracranial sites. Distant metastases of retinoblastomas are exceedingly rare, but basically known also in developed countries.2,3 Most affected site of distant metastases is the bone marrow, infiltrated by tumor cells spread with the blood flow.4,5
Conservative management of retinoblastoma: Challenging orthodoxy without compromising the state of metastatic grace. “Alive, with good vision and no comorbidity”
2019, Progress in Retinal and Eye ResearchCitation Excerpt :They are not commonly performed in early stages (IRSS stage 0 or 1) where the risk of harboring disseminated disease is considered minimal. These investigations, as well as skeletal scintigraphy are, however, indicated in case of symptoms (pain, neurologic manifestations), exteriorization of the disease or high-risk pathology features reported after enucleation (Azar et al., 2003; Barai et al., 2004; Karcioglu et al., 1997; Moscinski et al., 1996; Pratt et al., 1989). If conservative treatment is attempted, some groups advocate cytological evaluation of the cerebrospinal fluid in cases where the optic nerve cannot be visualized (Mallipatna et al., 2017).
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