Elsevier

Zeolites

Volume 19, Issue 1, July 1997, Pages 47-50

Original Articles
Development and Featuring of the Zeolitic Active Principle FZ: A Glucose Adsorbent

https://doi.org/10.1016/S0144-2449(97)00022-5Get rights and content

Abstract

The development of a zeolitic active principle called FZ that shows a high selectivity for glucose adsorption is described. FZ has been obtained by hydrothermal transformation of natural purified clinoptilolite. This principle has been physically and chemically characterized by using X-ray diffraction, infrared spectroscopy, and chemical analysis techniques.

Introduction

Individuals suffering from diabetes mellitus require an accurate control of blood glucose levels. Thus, in recent years, there are available on the market inhibitory medications[1]for the disaccharidase enzymes that restrain glucose absorption.

The results of much research have demonstrated that the natural clinoptilolite from the Tasajeras deposit (Cuba) does not produce biological damage to the human being.[2]The different active products obtained from this clinoptilolite by hydrothermal modification have particular biological interactions[3]through adsorption and ion exchange mechanisms.

Ching et al.[4]reported good results for the separation by diffusion of glucose from fructose in mixture, using a commercial CaY-type zeolite. Synthetic zeolites have been evaluated in toxicological tests without success. The instability in gastric and intestinal juices produces bioactive Si and Al, which accumulate in the kidneys and liver.[5]

The advantages of natural clinoptilolite are that it is a nontoxic material,[2]and that it has the possibility of tailoring its properties;[6]these are the bases of the present work. We designed a series of active products, obtained by ion exchange in hydrothermal conditions, to find the best for glucose-fructose separation in solutions at near physiological state. From the study emerges FZ, an Fe2+-NZ form, with a high adsorption yield of glucose against nonadsorption capacity for fructose.

This paper collects the results of the process of obtaining the zeolitic active principle known as FZ, which shows high glucose adsorption values in vitro as well as the physical and chemical prevalence of this new material.

Section snippets

Natural Zeolite

Natural purified zeolite (NZ) obtained from zeolitic rock from the Tasajeras deposit was used as raw material.[6]NZ chemical and mineral phases composition[7]are shown in Table 1. NZ is a mixture of clinoptilolite-heulandite and mordenite zeolites.

FZ Obtainment

FZ was obtained by hydrothermal transformation of NZ using solutions of USPXIII ferrous sulphate (FeSO4), with rigorously controlled concentration, temperature, and pH. The Fe2+ exchanges in the NZ structure was optimized by considering glucose

Glucose Adsorption by Zeolitic Active Principles

The preliminary tests to determine the glucose adsorptive capacity of the different zeolitic active principles[6]obtained by hydrothermal transformation of natural clinoptilolite show that FZ is the one factor to have a higher glucose adsorptive capacity. These results are shown in Table 2.

X-ray Diffraction

The analysis of the diffraction patterns obtained shows that the zeolitic phases involved correspond to clinoptilolite and mordenite characterized by their more intense peaks related to the interplanar

Conclusions

  • This study describes the preparation of a new zeolitic active material: Fe2+-containing clinoptilolite, which shows a high percentages of glucose capture in vitro.

  • It was demonstrated that the hydrothermal process used in the obtainment of FZ does not affect the content of zeolitic phases of the NZ sample used as a raw material.

  • The formation of CaSO42H2O was proved as a direct consequence of the ion exchange process produced by hydrothermal transformation from NZ to FZ.

  • The comparative studies

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  • Rodrı́guez-Fuentes, G. Ph.D. Thesis, CENIC-Cuba,...
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