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    Comparison of methotrexate monotherapy with a combination of methotrexate and etanercept in active, early, moderate to severe rheumatoid arthritis (COMET): a randomised, double-blind, parallel treatment trial . 
    The Lancet , Volume 372 , Issue 9636 , Pages 375 - 382
    P . Emery , F . Breedveld , S . Hall , P . Durez , D . Chang , D . Robertson , A . Singh , R . Pedersen , A . Koenig , B . Freundlich
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