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doi:10.1016/S0040-4039(98)02110-8 
Copyright © 1998 Published by Elsevier Ltd.
A divergent approach to the myriaporones and tedanolide: Enantioselective preparation of the common intermediate
Received 25 August 1998;
accepted 1 October 1998.
Available online 9 February 1999.
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Abstract
The tedanolide and myriaporone classes of natural products represent interesting targets for synthesis because of their structural similarity and biological activity. The asymmetric preparation of a potential common intermediate in the total synthesis of each of these targets is presented. The key step, a Zr-mediated allylation, allows for the efficient preparation of the hydroxypropionate structural unit.
