Elsevier

Phytochemistry

Volume 24, Issue 8, 1985, Pages 1825-1828
Phytochemistry

Alkaloids of Haemanthus kalbreyeri

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Abstract

The roots of Haemanthus kalbreyeri contain a new phenanthridone alkaloid, kalbretorine, and a new glucosyloxy alkaloid, kalbreclasine. Additionally, six known alkaloids, viz. haemanthamine, haemanthidine, hippadine, lycorine, narciclasine and pratorimine, previously reported from other Amaryllidaceous plants have now been isolated also from this species. Kalbretorine produced marked inhibition of growth and viability of S-180 tumour cells. Kalbreclasine caused significant mitogenic activation of splenic lymphocytes characteristic of immuno stimulants.

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Part 13 in the series “Chemical Constituents of Amaryllidaceae”. For part 12 see ref. [14].

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