Clinical and laboratory observation
Zinc supplementation in lactating women: Evidence for mammary control of zinc secretion*

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Cited by (34)

  • Zn status of sows and piglets as affected by diet and sow parity

    2015, Livestock Science
    Citation Excerpt :

    The absence of significant differences in colostrum and milk Zn concentrations in the present experiments suggests that sows regulate Zn secretion in colostrum and milk (McCormick et al., 2014), at least for the dietary Zn concentrations tested here. Colostrum and milk Zn concentration seem to be maintained over a wide range of dietary Zn intakes (Earle and Stevenson, 1965; Courtney Moore et al., 1984; Krebs, 1998; Kelleher and Lönnerdal, 2005), and only when Zn was fed at 3–4 times the recommended dose for sows, in colostrum and milk Zn concentrations increased (Kirchgessner et al., 1980). Other authors reported increased concentrations of Zn in sow milk and piglet liver, kidney and pancreas, accompanied by a decrease in Cu concentration in sow milk and piglet liver, pancreas and muscle when excessive dietary Zn (5000 ppm) was supplied (Hill et al., 1983a, 1983b).

  • Acne, pregnant women and zinc salts: A literature review

    2008, Annales de Dermatologie et de Venereologie
  • Molecular regulation of milk trace mineral homeostasis

    2005, Molecular Aspects of Medicine
    Citation Excerpt :

    During lactation, a substantial amount of Zn is taken up by the human mammary gland and secreted into milk (0.5–1 mg/d), facilitating the movement of almost twice the amount of Zn that is transferred daily across the placenta to the fetus during pregnancy (King, 2002), which illustrates the extraordinary activity of mammary gland Zn transport. Furthermore, milk Zn concentration is maintained over a wide range of dietary Zn intake (Moore et al., 1984; Krebs, 1998), which suggests that mammary gland Zn import and export are tightly coordinated in order to provide adequate Zn to the nursing infant. Although plasma Zn concentration increases throughout the normal course of lactation in both rodents and humans, milk Zn concentration declines (Keen et al., 1981); however, transport mechanisms that regulate this longitudinal decrease are not well understood.

  • Zinc in human milk

    2000, Nutrition Research
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Supported in part by grant AM 26657 from the National Institutes of Health.

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