Massive decline in lung liquid before vaginal delivery at term in the fetal lamb†
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Cited by (31)
Preterm birth affects both surfactant synthesis and lung liquid resorption actors in fetal sheep
2024, Developmental BiologyEstablishing functional residual capacity in the non-breathing infant
2013, Seminars in Fetal and Neonatal MedicineCitation Excerpt :However, whether or not lung liquid secretion rates and volumes decrease before labour onset is controversial. Some studies have reported a decrease [14–16], whereas others [17] have found no change if the pregnancy is not complicated by a reduction in amniotic fluid volumes. Furthermore, it is unclear how reductions in lung liquid secretion rates could reduce lung liquid volumes, as reductions in secretion rates simply reduce liquid loss via the trachea, resulting in no change in liquid volumes [9,10].
Elective Cesarean Section: Its Impact on Neonatal Respiratory Outcome
2008, Clinics in PerinatologyCitation Excerpt :We are still far from a complete understanding of the mechanisms by which fetal lungs are able to clear themselves of excessive fluid at birth [81]. It is clear, though, that traditional explanations relying on “Starling forces” and “vaginal squeeze” can only account for a fraction of the fluid absorbed [71,82–86]. Amiloride-sensitive sodium transport by lung epithelia through epithelial sodium channels (ENaC) has emerged as a key event in the transepithelial movement of alveolar fluid [72,74,75,78–80,87–90].
Developmental regulation of lumenal lung fluid and electrolyte transport
2007, Respiratory Physiology and NeurobiologyExpulsion of liquid from the fetal lung during labour in sheep
2007, Respiratory Physiology and NeurobiologyHypoxic Respiratory Failure in the Late Preterm Infant
2006, Clinics in PerinatologyCitation Excerpt :Understanding of the mechanisms(s) by which fetal lungs are able to clear themselves of excessive fluid at birth remains far from complete. It is clear though, that traditional explanations that relied on Starling forces and vaginal squeeze can account for only a fraction of the fluid absorbed [13–18]. Amiloride-sensitive sodium transport by lung epithelia through epithelial sodium channels (ENaC) has emerged as a key event in the transepithelial movement of alveolar fluid [19–27], and this appears to be a two-step process.
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