Elsevier

Vaccine

Volume 37, Issue 30, 9 July 2019, Pages 3974-3980
Vaccine

Review
Using economic and social data to improve veterinary vaccine development: Learning lessons from human vaccinology

https://doi.org/10.1016/j.vaccine.2018.10.044Get rights and content
Under a Creative Commons license
open access

Highlights

  • Socio-economic data are more widely used in human than veterinary vaccinology.

  • Exploring disease burden and intervention impacts will aid resource allocation.

  • The GBADs programme will assist us to better target interventions in animal health.

  • Large post-introduction studies can evaluate vaccine safety and effectiveness.

Abstract

The drivers of vaccine development are many and varied. They include, for example, recognition of the burden of a vaccine-targeted disease, prioritisation of the multiple problems associated with a disease, consideration of the differing socio-economic situations under which vaccines are used, the influence of advocacy groups, and assessment of the feasibility of large-scale vaccine manufacture and distribution. In the field of human health, data-driven development of vaccines is becoming increasingly common through the availability of reliable information on the Global Burden of Disease (GBD) and stringent evaluations of vaccination programmes utilising empirical data on costing and effectiveness, and standardised cost-effectiveness thresholds. The data generated from such analyses allow policymakers, implementing partners, industries and researchers to make decisions based on the best, and most contextually relevant, available evidence. In this paper, we wish to explore the current use of economic and social data for the development of veterinary vaccines. Through comparison with the development of human vaccines, we will look for opportunities in animal health sciences to better integrate socio-economic data and analyses into the process of veterinary vaccine selection, development, and field implementation. We believe that more robust animal health impact assessments could add value to veterinary vaccine development by improving resource allocation and animal disease management.

Keywords

Social data
Economic data
Socio-economic analysis
Cost-effectiveness
Post-introduction studies
Pharmacovigilance
Disease burden

Abbreviations

BNP
Bovine Neonatal Pancytopenia
DALYs
Disability Adjusted Life Years
GAVI
Global Alliance for Vaccines and Immunisation
GBADs
Global Burden of Animal Diseases
GBD
Global Burden of Disease
ICER
Incremental Cost-Effectiveness Ratio
PAHO
Pan-American Health Organization
QALYs
Quality Adjusted Life Years
VE
Vaccine Effectiveness
OIE
World Organisation for Animal Health
zDALYs
Zoonotic Disability Adjusted Life Years

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