Regulation of proliferation of rat mammary tumor cells by inhibitors of cyclooxygenase and lipoxygenase
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Bone metabolism and quality-of-life of postmenopausal women with invasive breast cancer receiving neoadjuvant hormonal therapy: Sub-analyses from celecoxib anti-aromatase neoadjuvant (CAAN) trial
2011, Journal of Steroid Biochemistry and Molecular BiologyCitation Excerpt :The therapeutic possibilities of COX-2 inhibition has been investigated since epidemiological studies suggested the inverse association between regular intake of nonsteroidal anti-inflammatory drugs (NSAIDs) and the breast cancer risk [31–33]. COX-2 inhibitors were found to be able to inhibit the carcinogenesis of mammary tumors in rodent models [34–37]. Celecoxib (CXB), a promising selective COX-2 inhibitor, demonstrated its chemopreventive ability in rodent models with breast cancer.
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2005, Prostaglandins Leukotrienes and Essential Fatty Acids
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