International Journal of Radiation Oncology*Biology*Physics
Brief communicationStereotactic radiosurgery as an adjunct to surgery and external beam radiotherapy in the treatment of patients with malignant gliomas
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Cited by (74)
Principles and Tenets of Radiation Treatment in Glioblastoma
2016, GlioblastomaApplications of Stereotactic Radiosurgery in Neuro-Oncology
2016, Handbook of Neuro-Oncology Neuroimaging: Second EditionStereotactic Radiosurgery for Intracranial Gliomas
2013, Neurosurgery Clinics of North AmericaCitation Excerpt :Although some reports argue for up-dosing fractionated radiotherapy,4 most reports would favor for a boost with SRS, trying to minimize radiation injury to the adjacent normal brain. Historically, many retrospective studies claimed feasibility and apparent efficacy of the combined radiation,5–8 which was supported by some,9,10 but not all,8,11 prospective studies. A prospective study conducted by Mehta and colleagues10 reported a 2-year survival rate of 28% in 31 patients with newly diagnosed glioblastoma treated with the conventional radiotherapy with an SRS boost, which was significantly superior to 9.7% in the previous Radiation Therapy Oncology Group (RTOG) study patients.
Secondary gliosarcoma with extra-cranial metastases: A report and review of the literature
2013, Clinical Neurology and NeurosurgeryCitation Excerpt :It allows additional radiotherapy for many patients who have already completed external beam radiotherapy in the past. Further study is still required to determine the exact role for stereotactic radiosurgery in the treatment of gliosarcoma [27,30]. Little is known about the response of metastatic GS to a traditional sarcoma-based chemotherapeutic regimen including an anthracycline.
Decision making and management of gliomas: Practical considerations
2012, Annals of OncologyCitation Excerpt :Several uncontrolled retrospective and prospective studies suggested improved survival when a SRS-boost was added to the conventional radiotherapy in newly diagnosed gliomas [53–57]. These data could, however, not be confirmed by other studies [58]. In a prospective multi-institutional, phase III randomized trial (RTOG 93-05), SRS was added to standard external beam RT and carmustine chemotherapy [59].
Systematic review of stereotactic radiotherapy for high-grade gliomas
2010, Cancer/Radiotherapie