Highly repeated short DNA sequences in the genome of Schistosoma mansoni recognized by a species-specific probe

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Abstract

A cloned 0.64-kb DNA sequence of Schistosoma mansoni contains 121-bp tandem repeats and comprises at least 12% of the schistosomal genome of both sexes. It exhibits a high degree of species specificity upon hybridization with Schistosoma haematobium and Schistosoma magrebowiei DNA, and could detect with high sensitivity schistosomal DNA sequences in infected snails.

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∗

Present address: Division of Infectious Diseases, Department of Medicine, Beth Israel Hospital, Boston, MA, U.S.A.

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