Autonomic neurotransmitters and trophic factors

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Abstract

Substantial changes to the classical view of two transmitters in the autonomic nervous system are discussed: there is now evidence that about 16 putative neurotransmitter substances exist; some transmitter substances coexist within single nerve terminals, and upon release may act as co-transmitters or as pre- or post-junctional neuromodulators, and autonomic nerves release ‘trophic factors’ which have long-term influences on development and regeneration. Thus these findings influence interpretation of the autonomic nervous system's function and pathophysiology.

References (34)

  • G. Burnstock

    Purinergic nerves

    Pharmacol. Rev.

    (1972)
  • G. Burnstock

    A basis for distinguishing two types of purinergic receptor

  • G. Burnstock

    Autonomic innervation and transmission

    Brit. Med. Bull.

    (1979)
  • G. Burnstock

    Past and current evidence for the purinergic nerve hypothesis

  • G. Burnstock

    Neurotransmitters and trophic factors in the autonomic nervous system

    J. Physiol. (Lond.)

    (1981)
  • G. Burnstock

    Ultrastructural identification of neurotransmitters

  • G. Burnstock

    Current approaches to development of the autonomic nervous system: clues to clinical problems

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