Experimental manipulations of eating: Advances in animal models for studying anorectic agents

doi:10.1016/0163-7258(87)90001-5

Pharmacology & Therapeutics

Volume 34, Issue 3, 1987, Pages 349-401

https://doi.org/10.1016/0163-7258(87)90001-5 Get rights and content

Abstract

The material set out in this text has been designed to show the wide range of procedures which have the capacity to modify eating behavior—to produce hyper- or hypophagia, to alter the profile of eating patterns, or to adjust dietary preferences and selection. Accordingly, in investigating anoretic drugs it seems necessary to observe the effects of drug actions in a variety of experimental models. This strategy will provide a more complete description of the effect of a drug, will throw light on the mechanism of action, and will provide a more realistic base for predicting the effects of drugs in man.

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^∗: Present address:d: Biopsychology Group, Psychology Department, University of Leeds, Leeds LS2 9JT, U.K.

^†: Present address: Bioscience Research Centre, Beecham Pharmaceuticals, Yew Tree Bottom Road, Epsom, Surrey KT18 5XQ, U.K.

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Experimental manipulations of eating: Advances in animal models for studying anorectic agents

Abstract

Pharmac. Biochem. Behav.

Brain Res.

Physiol. Behav.

Brain Res.

Pharmac. Biochem. Behav.

Neuroscience Biobehavioural Rev.

Physiol. Behav.

J. Nutr.

Life Sci.

Physiol. Behav.

Hormones Behaviour

Physiol. Behav.

Physiol. Behav.

Pharmac. Biochem. Behav.

Physiol. Behav.

Physiol. Behav.

Physiol. Behav.

J. Nutr.

Physiol. Behav.

Physiol. Behav.

Physiol. Behav.

Pharmac. Biochem. Behav.

Pharmac. Biochem. Behav.

Eur. J. Pharmac.

Psychiat. Clin. N. Am.

Brain Res. Bull.

Prog. Neuro-Psychopharmac.

Life Sci.

Pharmac. Biochem. Behav.

Neuropharmac.

Pharmac. Biochem. Behav.

Physiol. Behav.

Pharmac. Biochem. Behav.

Physiol. Behav.

Physiol. Behav.

Eur. J. Pharmac.

Life Sci.

Brain Res.

Comparative study of anorectic activity of d-amphetamine, chlorphentermine and fenfluramine in aurothioglucose obese and non-obese mice

Archs int. Pharmacodyn. Thér.

Brain mechanisms for offense, defense and submission

Behavl Brain Sci.

Overeating and obesity from damage to a noradrenergic system in the brain

Science, N.Y.

Diminished amphetamine anorexia and enhanced fenfluramine anorexia after mid-brain 6-hydroxydopamine

Psychopharmacology

Drug-produced obesity. Experience with chlorprozine, perphenazine and clopenthixol

Dan. med. Bull.

Regulation of protein intake by plasma amino acids

Adv. Nutr. Res.

Control of protein and energy intake: role of plasma amino acids and brain neurotransmitters

Can. J. Physiol. Pharmac.

Intact regulation of protein intake during the development of hypothalamic or genetic obesity in rats

Physiol. Behav.

Clozapine induces hyperphagia in undeprived rats

Life Sci.

Tails of stress-related behaviour: a neuropharmacological analysis

Tail-pinch induces eating in sated rats which appears to depend on nigro-striatal dopamine

Science, N.Y.

Circadian rhythms

Comparative study of anorectic activity of $d- amphetamine$ , chlorphentermine and fenfluramine in aurothioglucose obese and non-obese mice