Assessment of quality of life in patients with perennial allergic rhinitis with the French version of the SF-36 Health Status Questionnaire

doi:10.1053/ai.1994.v94.a54939

Journal of Allergy and Clinical Immunology

Volume 94, Issue 2, Part 1, August 1994, Pages 182-188

https://doi.org/10.1053/ai.1994.v94.a54939 Get rights and content

Abstract

Background and aim: Perennial allergic rhinitis may impair social life. General scales of quality of life (QOL) are used to detect the importance of social life impairment, but the reliability and validity of QOL measures should be tested in patients with perennial allergic rhinitis. The extent to which QOL scores differ in patients with rhinitis and healthy subjects is unknown. Methods: A cross-sectional study was carried out in 111 patients with moderate to severe perennial allergic rhinitis and 116 healthy subjects to assess the validity of a general QOL scale, the SF-36 Health Status Questionnaire. This scale is based on 36 items selected to represent nine health concepts (dimensions). The internal reliability of each dimension of the questionnaire was examined. The differences in QOL scores between patients with rhinitis and healthy subjects were studied. Results: Most QOL scores were highly reliable. There was a significant impairment in eight of nine QOL dimensions in patients with perennial allergic rhinitis in comparison with healthy subjects. Conclusions: The SF-36 Health Status Questionnaire allows discrimination between patients with perennial allergic rhinitis and healthy subjects. (J ALLERGYCLINIMMUNOL1994;94:182-8.)

Section snippets

Patients

One hundred eleven patients of both sexes with perennial allergic rhinitis, ranging in age from 18 to 50 years (mean ± SD: 31.5 ± 8.8 years), were recruited for the study by 11 allergists and five ear, nose, and throat doctors. To be included, patients had to show clinical evidence of perennial allergic rhinitis, which was investigated through suggestive symptoms (runny nose, itchy nose, sneezing, stuffy nose).

The clinical severity of these symptoms was scored on a 5-point scale ranging from no

Characteristics of the subjects

The demographic characteristics of healthy subjects and patients with rhinitis are shown in Table III. Although the mean ages and the male-to-female ratio were similar in both groups, the patients with rhinitis were significantly more educated than the healthy subjects. The duration of rhinitis ranged from 1 to 25 years (mean ± SD: 7.74 ± 5.78 years). The distribution of scores for each of the four rhinitis symptoms evaluated is presented in Fig. 1. In the rhinitis group 44% of the patients

DISCUSSION

The results of this study show that the SF-36 questionnaire, a generic health-related QOL scale, is sensitive enough to detect the impairments of patients affected by perennial allergic rhinitis in their daily activities and that this questionnaire is reliable in this population. Moreover, this study shows for the first time that perennial allergic rhinitis impairs the QOL of patients with moderate to severe rhinitis compared with healthy subjects.

QOL scales can be divided into generic scales,

Acknowledgements

We thank the following investigators for participating in this study: Dr. Anton (Allergist), Nantes; Dr. Arbez (Occupational doctor), Lyon; Dr. Boachon (ENT), Lyon; Dr. Camuzard (ENT), Nice; Prof. Colas (Allergist), Caluire; Dr. Cosset (Occupational doctor), Nantes; Dr. Dautel (Occupational doctor), Neuville s/Saone; Dr. Ducauchuis (ENT), Nantes; Dr. Durand Perdriel (Allergist), Nantes; Dr. Finet (Occupational doctor), Lyon; Dr. Fleury (Allergist), Lyon; Dr. Fontaine (Occupational doctor),

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^☆: From ^aServices des Maladies Respiratoires, Hopital Arnaud de Villeneuve, Montpellier; ^bLudwig Maximilians Universität München, Institut für Medizinische Psychologie Goethestraβe, München; ^cMAPI, S.A., Lyon; and ^dUCB S.A., Chemin du Foriest, Braine-l’Alleud, Belgique.

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Assessment of quality of life in patients with perennial allergic rhinitis with the French version of the SF-36 Health Status Questionnaire☆

Abstract

Section snippets

Patients

Characteristics of the subjects

DISCUSSION

Acknowledgements

Soc Sci Med

Development and testing of a new measure of health status for clinical trials in rhinoconjunctivitis

Clin Exp Allergy

Comparison of powder and aerosolized budesonide in perennial rhinitis: validation of rhinitis quality of life questionnaire

Ann Allergy

Quality of Life: assessment and application

Ciba Foundation Symposium

The Sickness Impact Profile: development and final revision of a health status measure

Med Care

The MOS 36-item Short-Form Health Survey (SF-36) I. Conceptual framework and item selection

Med Care

A Short-Form General Health Survey

The MOS 36-item Short-Form Health Survey (SF-36). II. Psychometric and clinical tests of validity in measuring physical and mental health constructs

Med Care

Reliability and validity in a patient population

Med Care