Brief communicationPersistence of the ability of amphetamine preexposure to facilitate acquisition of cocaine self-administration
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Amphetamine Usage, Misuse, and Addiction Processes: An Overview
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2016, Neuropathology of Drug Addictions and Substance Misuse Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants and International Aspects"Sexy stimulants": The interaction between psychomotor stimulants and sexual behavior in the female brain
2014, Pharmacology Biochemistry and BehaviorCitation Excerpt :Since the early observations that humans readily become addicted to d-amphetamine, a great deal of research has accumulated investigating d-amphetamine. Amphetamine acts as a positive reinforcer (Bevins et al. 1997; Piazza et al., 1990; Pierre and Vezina, 1997), and has been shown to enhance the reinforcing properties of other drug- (Horger et al., 1990; Piazza et al., 1990; Pierre and Vezina, 1997; Valadez and Schenk, 1994) and natural-rewards (e.g., food, sex; (Fiorino and Phillips, 1999; Nocjar and Panksepp, 2002)). Previous experience with d-amphetamine has been shown to facilitate: 1) the acquisition and rate of sexual behavior in sexually naïve male rats (Fiorino and Phillips, 1999; Fiorino and Phillips, 1999), 2) the acquisition of drug self-administration (Mendrek et al., 1998; Piazza et al., 1990) and 3) the development of a CPP associated with other drugs of abuse (Lett 1989).
Alpha1-adrenergic drugs affect the development and expression of ethanol-induced behavioral sensitization
2013, Behavioural Brain ResearchCitation Excerpt :The repeated drug exposure enhances the capacity to evoke subsequent conditioned place preference, demonstrated as either the need of lower drug doses, or fewer conditioning trials, to establish conditioned place preference [11–18]. Drug self-administration is also enhanced by repeated drug pretreatment, indicated by either its faster acquisition or acquisition at lower doses [19–26]. Besides, pretreatment with other stimulants, such as amphetamine, also accelerated the escalation of cocaine self-administration, when animals were allowed long daily access to the drug [27].
Expression and resilience of a cocaine-conditioned locomotor response after brief and extended drug-free periods
2012, Behavioural Brain Research