Iodine-123 production for radiopharmaceuticals—XX: Excitation functions of the 124Te(p, 2n)123I and 124Te(p, n)124I reactions and the effect of target enrichment on radionuclidic purity

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Abstract

The excitation functions for the 124Te(p, 2n)123I and 124Te(p, n)124I reactions were determined with thin films of 99.87% and 91.86% isotopically enriched 124Te. The production rates and the optimum fractions of the excitation functions for obtaining the maximum radiochemical purity of 123I with the different isotopic enrichments of 124Te were established. Targetry, radiochemistry and a quantitative procedure for recovery of 124Te are to be described in a subsequent paper. The 124Te(p, 2n)123I reaction on ultrahigh enrichment 124Te is a satisfactory and economical production method on cyclotrons with particle energies or beam intensities too low to produce 123Xe as a source of high-purity iodine-123.

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    For earlier papers in this series, see ref. 1. All enquiries should be directed to R. M. Lambrecht.

    Research performed at Brookhaven National Laboratory under contract with the U.S. Energy Research and Development Administration, and partially supported by NIH Grant No 5. P41 RR00657.

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