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Chemical Kindling
2006, Models of Seizures and EpilepsyCharacterization of the distribution of the cocaine priming threshold and the effect of SCH23390
2002, Brain ResearchCitation Excerpt :Repeated measurement of the cocaine priming threshold is similar to the repeated measurement of the cocaine-induced seizure threshold. However, with repeated measurement the seizure threshold progressively declined [19,27]. This was interpreted as the development of sensitization to cocaine-induced seizures.
Pyriform cortex β-waves: Odor-specific sensitization following repeated olfactory stimulation
2001, Brain ResearchCitation Excerpt :The results obtained in the chlorpromazine-treated rats also demonstrate that blockade of dopaminergic and α-adrenergic receptors by chlorpromazine [2] does not prevent β-wave sensitization. Although the olfactory sensitization demonstrated here is similar in certain respects to electrically-induced kindling [13], long-term potentiation [3,4] and sensitization to drugs [9,23,27,28,30,34] it also differs from these phenomena in several ways. First, odor-induced sensitization is perhaps a more physiological phenomenon than electrically or chemically induced-kindling or sensitization to drugs.
Double-blind comparison of carbamazepine and placebo for treatment of cocaine dependence
1995, Drug and Alcohol Dependence