Original articleInvolvement of the limbic system in multiple sclerosis patients with depressive disorders
References (27)
- et al.
Emotional responses to multiple sclerosis
Psychosomatics
(1981) - et al.
Frontal cortex and basal ganglia metabolic rates assessed by positron emission tomography with FDG in affective illness
J Affect Disord
(1986) - et al.
Depression in multiple sclerosis
Gen Hosp Psychiatry
(1987) A clinico-experimental investigation into the psychologic aspects of multiple sclerosis
J Nerv Dis
(1952)- et al.
Reduction of prefrontal cortex glucose metabolism common to three types of depression
Arch Gen Psychiatry
(1989) - et al.
Lesion analysis in neuropsychology
(1989) - et al.
Multiple sclerosis: MRI and clinical correlation
Am J Neuroradiol
(1986) - et al.
Psychotic illness in multiple sclerosis
A clinical and magnetic resonance imaging study
Br J Psychiatry
(1992) - et al.
Temporal lobe involvement in multiple sclerosis patients with psychiatric disorders
Arch Neurol
(1987) Rating neurologic impairment in multiple sclerosis: An expanded disability status scale EDSS
Neurology
(1983)
Technezium-99m d, I-HM-PAO: A new radiopharmaceutical for SPECT imaging of regional brain perfusion using SPECT: A comparison with iodine-123 HIPDM
J Nucl Med
Neuropsychological Assessment
Psychiatric morbidity in patients with clinically isolated lesions of the type seen in multiple sclerosis: A clinical and MRI study
Cited by (72)
Association between limbic system lesions and anxiety in persons with multiple sclerosis
2023, Multiple Sclerosis and Related DisordersThe patient repeats itself… and so does the history?
2019, Pratique Neurologique - FMCRegional gray matter atrophy in relapsing remitting multiple sclerosis: Baseline analysis of multi-center data
2015, Multiple Sclerosis and Related DisordersCitation Excerpt :Magnetic resonance imaging (MRI) is the most common modality for atrophy quantification and lesion load in MS. A number of studies suggest that regional atrophy is a more sensitive indicator of the disease than global atrophy. Deep GM structures appear to atrophy early on in the disease (Audoin et al., 2010; Bergsland et al., 2012; Charil et al., 2007; Fisher et al., 2008; Fisniku et al., 2008; Mesaros et al., 2008; Pagani et al., 2005; Raz et al., 2010; Sabatini et al., 1996; Sepulcre et al., 2006). Deep GM atrophy is found to correlate with clinical disease markers such as fatigue (Niepel et al., 2006), cognition (Brass et al., 2006; Houtchens et al., 2007; Nocentini et al., 2014), expanded disability status scale (EDSS) score (Bakshi et al., 2001; Prinster et al., 2010; Tao et al., 2009) and MR derived measures such as T2 and T1 lesion loads (Ceccarelli et al., 2009; Tao et al., 2009).
Multiple Sclerosis and Depression: A Neuroimmunological Perspective
2010, NeuroImmune BiologyCitation Excerpt :Major cognitive impairment correlates strongly with disease burden, but ties marginally at best to depression [17, 19, 22, 23, 28, 29, 31, 34, 52, 55, 81, 82]. Most find no correlation between depression and disease duration or extent of disability [5, 8, 12, 21, 30, 31, 33, 41, 50, 65, 81, 82], but not all [17, 21, 78, 81]. Elderly MS patients have fewer depressions, suggesting that depression may actually correlate negatively with disease duration [30].
Transcranial sonography in depression
2010, International Review of NeurobiologyCitation Excerpt :Depression is a frequent finding in multiple sclerosis (MS), with a prevalence of about 40% (Minden et al., 1990). Disconnection between subcortical and cortical areas associated with the limbic system has been proposed as a pathogenic mechanism of depression in MS (Sabatini et al., 1996). In the study of Berg and co-workers (Berg et al., 2000a), echogenicity of the BR was rated in 78 patients, fulfilling the criteria for definite multiple sclerosis (Poser et al., 1983).
Deep gray matter atrophy in multiple sclerosis: A tensor based morphometry
2009, Journal of the Neurological Sciences