Biochemical and Biophysical Research Communications
Volume 131, Issue 2, 16 September 1985, Pages 543-550
Novel antigenic specificity involving the blood group antigen, Lea, in combination with onco-developmental antigen, SSEA-1, recognized by two monoclonal antibodies to human milk-fat globule membranes
References (40)
- et al.
Biochim. Biophys. Acta
(1967) - et al.
The Lancet
(1982) - et al.
Lancet
(1982) - et al.
Molec. Immun
(1983) - et al.
J. Biol. Chem
(1984) - et al.
FEBS Letts
(1981) - et al.
J. Biol. Chem
(1983) - et al.
Biochim. Biophys. Acta
(1976) - et al.
J. Biol. Chem
(1984) - et al.
Biochem. Soc. Transact
(1984)
J. Biochem
(1982)
Eur. J. Biochem
(1977)
Int. J. Cancer
(1981)
Virchows Arch. (Pathol. Anat)
(1982)
Somatic Cell Genet
(1983)
Int. J. Cancer
(1984)
Biochem. Soc. Trans
(1983)
Carbohydr. Res
(1983)
Cited by (20)
Anti-Le<sup>a</sup> monoclonal antibody SPM 522 recognizes an extended Le<sup>a</sup> epitope
2022, Bioorganic and Medicinal ChemistryCitation Excerpt :The LeaLex TACA also displays epitopes selectively recognized by two other mAbs, 115C2 and 11SG3, raised against human milk-fat globule membranes.8 Since these mAbs were also shown to react weakly with the non-fucosylated lacto-N-tetraose (LNT) backbone (Table 1), it was suggested that they recognize an internal epitope within the LeaLex structures.8 As a cell surface epitope specific to cancer cells and a prognostic marker for carcinomas,2–4,6,9–11 the epitope recognized by mAb 43-9F is of great interest to develop LeaLex-based cancer immunotherapeutics.
Recognition of type 1 chain oligosaccharides and lacto-series glycolipids by an antibody to human secretory component
1995, Archives of Biochemistry and BiophysicsCancer-associated carbohydrates identified by monoclonal antibodies
1990, Human PathologyAberrant Glycosylation In Tumors And Tumor-Associated Carbohydrate Antigens
1989, Advances in Cancer Research
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HCG is supported by the Leukaemia Research Fund of Great Britain.
Copyright © 1985 Published by Elsevier Inc.