Isolation of a porcine intestinal peptide with C-terminal somatostatin

https://doi.org/10.1016/0006-291X(78)91218-4Get rights and content

Abstract

A peptide showing somatostatin-like immunoreactivity has been isolated from acid extracts of porcine upper small intestine. Purification was followed by radioimmunoassay, high pressure liquid chromatography, thin layer chromatography and isotachophoresis. Preliminary chemical characterization shows that it has N-terminal serine and that it is composed of somatostatin extended from its N-terminus by an additional peptide.

References (19)

  • W. Vale et al.

    Metabolism

    (1976)
  • J.A. Chayvialle et al.

    Gastroenterology

    (1978)
  • K.R. Woods et al.

    Biochim. Biophys. Acta

    (1967)
  • S. Moore

    J. Biol. Chem

    (1963)
  • P. Brazeau et al.

    Can. J. Biochem

    (1974)
  • R. Burgus et al.
  • A.V. Schally et al.

    Biochem

    (1976)
  • W. Vale et al.

    Rec. Prog. Horm. Res

    (1975)
  • M. Broenstein et al.

    Endocrinol

    (1975)
There are more references available in the full text version of this article.

Cited by (60)

  • Gastrointestinal Hormones

    2018, Physiology of the Gastrointestinal Tract, Sixth Edition
View all citing articles on Scopus
View full text