Clinical and Histopathologic Classification of Retinal Dysplasia

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    • Peters anomaly in cri-du-chat syndrome

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      It may also result from gene mutation.7 The incidence of retinal dysplasia has not previously been reported although it may be similar to that of retinoblastoma.7 Two authors cumulatively screened 66 patients with Peters anomaly and none were found to exhibit retinal dysplasia.5,6

    • Special Senses

      2015, Jubb, Kennedy & Palmer's Pathology of Domestic Animals: Sixth Edition
    • Unilateral sporadic retinal dysplasia: Results of histopathologic, immunohistochemical, chromosomal, genetic, and VEGF-A analyses

      2011, Journal of AAPOS
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      Others have suggested that abnormalities in the developmental sequence of programmed cell death (apoptosis), misdirected regenerative activity, or injuries to the retina occurring prepartum may play a role in retinal dysplasia.5,17 Dysplasia is not encountered as a reparative response in the adult mature retina.1,3-5 The histopathologic hallmark is the formation of pseudorosettes surrounded by extensive gliosis.1,3,16,17

    • Pathology of the Retina and Vitreous

      2022, Albert and Jakobiec's Principles and Practice of Ophthalmology: Fourth Edition
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    This work was supported by Public Health Service Grant EY-00108-03 and the Connecticut Lions Eye Research Foundation, Inc.

    Reprint requests to Daniel M. Albert, M.D., Department of Ophthalmology and Visual Science, Yale University School of Medicine, 333 Cedar Street, New Haven, Connecticut 06510.

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