Coupling between the heart and arterial system in heart failure
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Cited by (20)
Ventricular-arterial coupling, remodeling, and prognosis in chronic heart failure
2013, Journal of the American College of CardiologyCitation Excerpt :For maximal cardiac work, power, and efficiency, the coupling ratio of Ea/Ees typically resides between 0.5 and 1.2 (15,16). In failing hearts, this ratio increases as cardiac function declines and arterial load increases to maintain systolic pressure (17–20). At excessively high ratios, ventricular-vascular matching is significantly compromised, leading to inefficient and ineffective contraction (21).
Characterizing the right ventricle: Advancing our knowledge
2012, American Journal of CardiologyCitation Excerpt :In the normal LV, the aorta acts as an energy reservoir during systole and delivers energy back during diastole, which allows the LV to be relatively well coupled with the aorta. Studies in multiple animal models and humans have demonstrated that, despite the pulsatile nature of LV pump function, virtually all the energy expended is ultimately converted into flow energy as a consequence of the elastic recoil of the aorta.36,37 In contrast, in the RV 25%–40% of energy used by the RV is not converted to flow.38,39
Chronic cardiac failure: Physiology and treatment
2010, Paediatric CardiologyArterial elastance and heart-arterial coupling in aortic regurgitation are determined by aortic leak severity
2002, American Heart JournalCitation Excerpt :For all other cases, pump efficiency is lower than the theoretically predicted value based on Ea/Emax. The use of effective arterial elastance and of Ea/Emax has been promoted by theoretical and experimental studies linking Ea/Emax to LV mechanico-energetics.3,4,6-10,12 Note, however, that Ea/Emax is mainly a “geometrical” parameter related to ventricular volume.