Myometrial tumours
Section snippets
Ethnicity
Age-adjusted uterine leiomyomata rates among Black women are two-to-three times greater than corresponding rates among Caucasians. Higher rates among the Black population are evident at all ages. The rates among Hispanic and Asian women appear to be similar to those among Caucasians.
Age and Parity
Regardless of the method of diagnosis, the risk of leiomyomata increases as the age of menarche decreases. Postmenopausal women are at a 70–90% reduced risk for uterine fibroids. Women who have had a live born child
Clinical presentation of leiomyomas
It has been estimated that at least 50% of women with fibroids are asymptomatic.
Management options for leiomyomas
Small asymptomatic myomas require observation only. Surgical intervention for a leiomyoma based on size alone is also not justified. The risk of malignant transformation of uterine fibroids has been reported to range from 0.29% to 1%. There are no data to show that the rate of growth of a myoma is related to the incidence of malignancy.
Epithelioid smooth muscle cell
These tumours are exceedingly rare, and therefore their behaviour, malignant potential and optimal management are not clearly defined. They are predominantly or entirely composed of polygonal cells and have been referred to as leiomyoblastomas and epithelioid and clear cell muscle tumours. Necrosis is a prominent feature when the lesions are malignant, and they tend to pursue an aggressive course. Therefore when suspected they should be treated aggressively as for leiomyosarcomas (see below).
Leiomyomatosis
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Cited by (2)
Awareness and knowledge of uterine fibroid among women in Kerala, India
2022, International Journal of Public Health Science