Mild cognitive impairment: An opportunity to identify patients at high risk for progression to Alzheimer's disease
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The effects of herbal medicine (Jujadokseo-hwan) on quality of life in patients with mild cognitive impairment: Cost-effectiveness analysis alongside randomized controlled trial
2023, Integrative Medicine ResearchCitation Excerpt :Although not all patients progress to dementia, about 50% of patients with MCI develop dementia within three years and about 80% develop dementia within six years15. The major treatment strategy for MCI is disease-modifying, which can reduce the prevalence of dementia26-28. Interventions targeting biomarkers, including beta-amyloid plaques, neurofibrillary tangles, and inflammation, that contribute to neurodegeneration are theoretically considered as a potential pharmacotherapy for MCI29.
A Preliminary Study of an Experiment to Activate Brain Functions in the Elderly
2023, Procedia Computer ScienceStructural brain characteristics and gene co-expression analysis: A study with outcome label from normal cognition to mild cognitive impairment
2022, Neurobiology of Learning and MemoryCitation Excerpt :Mild cognitive impairment (MCI) is a transition state between normal cognition and Alzheimer’s disease (AD) (Morris, Storandt, Miller, Mckeel, Price, Rubin, and Berg, 2001; Stephan, Hunter, Harris, Llewellyn, Siervo, Matthews, and Brayne, 2012). MCI entails more cognitive and memory decline than normal ageing (Levey, Lah, Goldstein, Steenland, and Bliwise, 2006). Longitudinal studies found that some elderly people with normal cognition (NC) maintained an NC state, and some elderly people developed MCI during follow-up (Morris and Price, 2001).
Resting EEG spectral slopes are associated with age-related differences in information processing speed
2022, Biological PsychologyCitation Excerpt :Forty-nine participants were recruited for the study: healthy young adults (YA; <35 y; n = 22); cognitively healthy older adults (OA; >59 y; n = 24); and older adults with mild cognitive impairment (MCI; n = 3) following approval of the University Institutional Review Board. We originally planned to recruit a comparable sample of older adults with amnestic MCI, which is considered a prodrome of Alzheimer’s disease (Levey, Lah, Goldstein, Steenland & Bliwise, 2006). This sample would allow for comparison of neurological changes between neurologically healthy older adults and those with MCI.