Biochimica et Biophysica Acta (BBA) - Biomembranes
Volume 1508, Issues 1–2, 23 November 2000, Pages 210-234
ReviewSurface active drugs: self-association and interaction with membranes and surfactants. Physicochemical and biological aspects
Under an Elsevier user license
open archive
Keywords
Surface active drug
Drug self-association
Drug–membrane interaction
Drug–surfactant interaction
Membrane solubilization
Drug delivery
Abbreviations
AmB, amphotericin B
BS, bile salt
CAD, cationic amphiphilic drug
CD, circular dichroism
cmc, critical micellar concentration
CPZ, chlorpromazine
DBC, dibucaine
DOC, deoxycholate
DSC, differential scanning calorimetry
EPR, electron paramagnetic resonance
GI, gastrointestinal
HHB, hydrophilic–hydrophobic balance
LA, local anesthetic
Lyso PC, lysophosphatidylcholine
MM, mixed micelle
NMR, nuclear magnetic resonance
P, partition coefficient
PC, phosphatidylcholine
PEG, polyethylene glycol
PM, polymeric micelle
POE, polyoxyethylene
RBC, red blood cell
RES, reticuloendothelial system
SDS, sodium dodecyl sulfate
TFP, trifluoperazine
TI, therapeutic index
TTC, tetracaine
Cited by (0)
Copyright © 2000 Elsevier Science B.V. All rights reserved.