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Nodules sur foie de cirrhose : quelle imagerie ? pourquoi ? comment ?Imaging nodules within cirrhotic liver: How do I do it?

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Résumé

La cirrhose est une affection chronique du foie, qui associe la présence d’une nécrose parenchymateuse diffuse, le développement d’une réaction fibreuse et enfin l’apparition d’une régénération nodulaire. Cette régénération nodulaire aboutit à la transformation progressive de nodules régénératifs en nodules dysplasiques, puis en nodules de carcinome hépatocellulaire (CHC). L’amélioration de la survie à 5 ans d’un patient atteint de CHC tient à son éligibilité pour la transplantation hépatique. Nous détaillerons l’aspect en imagerie non invasive des nodules sur foie de cirrhose, afin de répondre à ces questions simples concernant les nodules sur foie de cirrhose : quelle imagerie ? pourquoi ? comment ?

Abstract

Cirrhosis is a chronic liver disease characterized by the presence of diffuse parenchymal necrosis, reactive fibrosis and nodular regeneration. These regenerative nodules may evolve into dysplastic nodules and finally nodules of hepatocellular carcinoma (HCC). Improved survival of cirrhotic patients with HCC depends on eligibility to liver tranplantation. The purpose of this paper is to review the imaging features of liver nodules within cirrhotic liver and to propose the imaging strategies when considering the possibility of liver transplantation.

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