A novel murine model of aging, Senescence-Accelerated Mouse (SAM)
References (43)
- et al.
Purification and characterization of a senile amyloid-related antigenic substance (apo SASSAM) from mouse serum
J. Biol. Chem.
(1986) - et al.
Development of congenic strains of mice carrying amyloidogenic apolipoprotein A-II (Apoa2c): Apoa2c reduces the plasma level and the size of high density lipoprotein
FEBS Lett.
(1993) - et al.
Grading score system: a method for evaluation of the degree of senescence in Senescence Accelerated Mouse (SAM)
Mech. Ageing Dev.
(1984) - et al.
Persistent vascular system in age-related cataract in a SAM strain of mouse
Exp. Eye Res.
(1993) - et al.
Accelerated aging of dermal fibroblast-like cells from Senescence-Accelerated Mouse (SAM). I. Acceleration of population aging in vitro
Mech. Ageing Dev.
(1994) - et al.
Chronic food restriction modulates the advance of senescence in Senescence Accelerated Mouse (SAM)
J. Nutr.
(1985) Animal models in aging research
- et al.
Age-related changes in learning and memory in the senescence-accelerated mouse (SAM)
Physiol. Behav.
(1986) - et al.
Acceleration of chromosome aberrations in senescence-accelerated strains of mice
Mutat. Res.
(1990) - et al.
Localization of atrophyprone areas in the aging mouse brain: comparison between the brain atrophy model SAM-P/10 and the normal control SAM-R/1
Neuroscience
(1994)
Effective intervention of low peak bone mass and bone modelling in the spontaneous murine model of senile osteoporosis, SAM-P/6, by Ca supplement and hormone treatment
Bone
(1994)
A new murine model of accelerated senescence
Mech. Ageing Dev.
(1981)
Spontaneous age-associated amyloidosis in Senescence-Accelerated Mouse (SAM)
Mech. Ageing Dev.
(1982)
Modification of strain-specific femoral bone density by bone marrow chimerism in mice. A study on spontaneously osteoporotic mouse (SAM-P/6)
Bone
(1989)
Cross-mating study on bone mass in the spontaneously osteoporotic mouse (SAM-P/6)
Bone Miner.
(1993)
Effects of dietary restriction on age-related immune dysfunction in the Senescence Accelerated Mouse (SAM)
J. Nutr.
(1990)
Dietary protein sources modulate the advance of senescence in the Senescence Accelerated Mouse (SAM)
J. Nutr.
(1993)
Amplification of extrachromosomal small circular DNAs in a murine model of accelerated senescence
Mech. Ageing Dev.
(1985)
Age-related morphological changes in the brains of Senescence-Accelerated Mouse (SAMP8)
Age related changes in the temporomandibular joint of the Senescence Accelerated Mouse (SAM): SAM-P/3 as a new murine model of degenerative joint disease
Am. J. Pathol.
(1989)
Diseases of aging
Cited by (98)
Senescence-accelerated mouse prone 8 (SAMP8) mice exhibit reduced entoconid in the lower second molar
2021, Archives of Oral BiologyEnvironmental enrichment improves hypomyelination, synaptic alterations, and memory deficits caused by tooth loss in aged SAMP8 mice
2021, Archives of Oral BiologyCitation Excerpt :SAMP8 mice develop normally up to 6 months of age, but exhibit accelerated senescence along with age-associated pathologic changes, behavioral alterations, and cognitive deficits, and a shortened lifespan of approximately 12 months compared with 2–3 years for other strains (Takeda et al., 1994). SAMP8 mouse is widely used as an animal model of human Alzheimer disease (Takeda et al., 1994). In this study, we used aged male SAMP8 mice (8 months old; n = 48).
Oxidative stress and the senescence acceleration in senescence-accelerated mouse P10 (SAMP10)
2020, Aging: Oxidative Stress and Dietary AntioxidantsReversal of age-associated frailty by controlled physical exercise: The pre-clinical and clinical evidences
2019, Sports Medicine and Health Science
Copyright © 1994 Published by Elsevier Ireland Ltd.