Original articleMacular Telangiectasia Type 1: Capillary Density and Microvascular Abnormalities Assessed by Optical Coherence Tomography Angiography
Section snippets
Subjects
This observational case series adhered to the tenets of the Declaration of Helsinki and Swiss federal regulations and was approved by the local Ethics Committee of the Swiss Department of Health (CER-VD no. 19/15). The study was conducted from June 1 to October 1, 2015, at Jules-Gonin Eye Hospital, Lausanne, Switzerland.
Medical records, optical coherence tomography (OCT), OCTA, FA, and indocyanine green angiography (ICGA) images from 7 consecutive subjects presenting with MT type 1 were
Results
There was no difference between the 7 patients presenting MT type 1 and the 12 healthy controls in terms of age (57.1 ± 10.2 vs 57.8 ± 6.9 years, P >.99) and sex (all male subjects).
Discussion
With OCTA, telangiectasic microaneurysms typical of MT type 1 were identified as focal dilations of the microvasculature. Although OCTA detected fewer lesions than FA in each affected eye, OCTA showed that telangiectasias were exclusively located in the deep capillary plexus. Moreover, in MT type 1 eyes the density of the macular capillary network was reduced in both superficial and deep plexuses, as compared to fellow and healthy control eyes, and the capillary network density of both plexuses
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