Original articleComparison of Exudative Age-related Macular Degeneration Subtypes in Japanese and French Patients: Multicenter Diagnosis With Multimodal Imaging
Section snippets
Methods
We retrospectively reviewed the medical records of 99 eyes of 99 consecutive patients who visited the Department of Ophthalmology, Kyoto University Hospital with a tentative diagnosis of neovascular AMD (Kyoto cases) and 95 eyes of 85 patients with presumed neovascular AMD at Centre d’Ophtalmologie de Paris (Paris cases). All patients underwent comprehensive ophthalmic examinations, including the measurement of best-corrected visual acuity, intraocular pressure testing, indirect ophthalmoscopy,
Results
This study consisted of 99 consecutive eyes of 99 Japanese patients and 95 consecutive eyes of 85 French patients with presumed neovascular AMD. One eye from among the French was excluded from the study because of angiographic images of low quality. The mean age of the 99 Japanese patients (70 men and 29 women) was 74.0 ± 8.9 years, and all patients were ethnically Japanese. The mean age of the 85 French patients (45 men and 40 women) was 73.5 ± 7.9 years, and 98% were white.
The “first-step
Discussion
In the present study, we addressed several gaps in the literature. First, our initial purpose was to try to determine whether the subtype diagnosis of exudative AMD can be made based on the results of fundus photography and FA only, and whether current multimodality diagnostic devices could help to enhance the accuracy of subtype diagnosis. We compared the results of “first-step diagnosis” with fundus photography and FA only to the results of “second-step diagnosis” with multimodality
Gabriel Coscas was trained at University of Paris, established the Department of Ophthalmology in University Paris XII, and served as Professor and Chairman until 1999. He devoted most of his activity on macular diseases. President of French Retina Society. He organized the first randomized clinical trial on macular photocoagulation for age-related macular degeneration in France. Author and co-author of over 450 peer-review papers and a founding member of Global Alliance against Trachoma at WHO.
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Cited by (0)
Gabriel Coscas was trained at University of Paris, established the Department of Ophthalmology in University Paris XII, and served as Professor and Chairman until 1999. He devoted most of his activity on macular diseases. President of French Retina Society. He organized the first randomized clinical trial on macular photocoagulation for age-related macular degeneration in France. Author and co-author of over 450 peer-review papers and a founding member of Global Alliance against Trachoma at WHO.
Kenji Yamashiro is an Assistant Professor of Ophthalmology at Kyoto University, Kyoto, Japan. He received MD and PhD from Kyoto University, and joined Dr Anthony Adamis' lab in Massachusetts Eye and Ear Infirmary in Boston from 2001 to 2003. He is an author and co-author of over 100 peer-review papers and currently the chief of the Macula Service of Kyoto University Hospital. His interests include clinical and genetic research on macular diseases.