Original articleComparison of Outcomes of Lamellar Keratoplasty and Penetrating Keratoplasty in Keratoconus
Section snippets
Methods
A comparative cohort study was performed in which clinical data were retrieved from computerized database of the prospective Singapore Corneal Transplant Study.1 A total of 168 keratoconus patients underwent corneal grafts between January 1991 and December 2006 at the Singapore National Eye Centre. A cut-off at December 2006 allowed for a minimum follow-up of 6 months, leaving 164 patients. Of these 164 patients, 21 patients who had incomplete follow-up and 18 cases of automated lamellar
Patient Data
One hundred and twenty-five corneal grafts comprising 100 PK, 11 DALKm, and 14 DALKa procedures were included in the study. There were more patients of Indian ethnic origin (39.8%) than other ethnic groups. This deviates from the ethnic ratio in Singapore, although statistical significance was not achieved (P = .16). There was a preponderance of males (P = .44). Fifty-five percent of grafts were to the right eye and 45% of grafts were to the left eye. The mean follow-up period with standard
Discussion
Recent studies have shown that the Anwar technique for DALK achieved better postoperative results in terms of improved VA and reduced complications than PK and older forms of DALK techniques, for example, manual DALK.11, 12, 13, 14, 15, 16 Our study shows that DALKa, that is, the modified Anwar technique, performed as well as PK with respect to postoperative mean BSCVA, best BSCVA achieved, and percentage of cases achieving good postoperative BSCVA. In addition, our DALKa cases attained higher
Dr Daphne Han received her MBBS degree from The University of Melbourne, Australia and completed her medical internship in England. She completed her Ophthalmology residency at the Singapore National Eye Centre, where she is currently an Associate Consultant in Cataract and Refractive Surgery.
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Cited by (219)
Large-Diameter Modified Big-Bubble Deep Anterior Lamellar Keratoplasty in Post–Radial Keratotomy Eyes
2023, American Journal of OphthalmologyDeep anterior lamellar keratoplasty (DALK) interface neovascularization: An unusual complication
2023, Journal Francais d'OphtalmologieDescemetic Deep Anterior Lamellar Keratoplasty versus Penetrating Keratoplasty in Advanced Keratoconus: Comparison of Visual and Refractive Outcomes
2024, Therapeutics and Clinical Risk ManagementMore support for deep anterior lamellar keratoplasty over penetrating keratoplasty for keratoconus, but questions remain
2024, British Journal of Ophthalmology
Dr Daphne Han received her MBBS degree from The University of Melbourne, Australia and completed her medical internship in England. She completed her Ophthalmology residency at the Singapore National Eye Centre, where she is currently an Associate Consultant in Cataract and Refractive Surgery.
See accompanying Editorial on page 629.