Potentized homoeopathic drugs act through regulation of gene-expression: a hypothesis to explain their mechanism and pathways of action in vitro
References (44)
- et al.
A hypothesis on the nature of homoeopathic potencies
Br Hom J
(1979) Microdose effects of drugs and chemicals on the enzymes urease, diastase and trypsin
Br Hom J
(1987)- et al.
Parallel effects of Pulsatilla and exogenous leutocyclin on the rat ovary, uterus and thyroid
Br Hom J
(1978) - et al.
Antiviral efficacy of homeopathic drugs against animal viruses
Br Hom J
(1985) - et al.
Comparison of wheat and yeast as in vitro models for investigating homoeopathic medicines
Br Hom J
(1983) Research in homeopathy — a bibliography compiled and annotated by Dr. P. Fisher
(1991)Microdose paradox — a new concept
J Am Inst Hom
(1965)Physikalische Wirkungen hochverdunnter potenzierter Substanzen
Die Naturwissenchaften
(1941)- et al.
Modern instrumentation for the evaluation of homeopathic drug structure
J Am Inst Hom
(1966) Nuclear magnetic resonance studies of succussed solutions — a preliminary report
J Am Hom Assoc
(1975)
Dielectric strength testing of homeopathic dilutions of HgC12
J Am Inst Hom
Etude des dilutions homeopathiques par effect Raman-Laser
Ann Hom Franc
Etude de l'action de chaleurs sur les dilutions Hahnemanniennes par spectrometrie Raman
Ann Hom Franc
Physics Teacher
A working hypothesis for homeopathic microdiluted remedies
Berlin J Res Hom
Physico-chemico study of homoeopathic solutions
Coherent dynamics in water
A thermodynamic model of the organism conducive to homeopathy and a hypothesis on the wavelike behaviour of the homeopathic remedy
Increase in serotonin and dopamine metabolites in mouse hypothalamus following oral administration of Agaricus muscarius 12, a homeopathic drug
Sci Culture
Influence of dopamine agonists and an opiate antagonist induced catalepsy as tested by a new method
Arch Int Pharmacodyn Ther
Influence of homoeopathic drugs on neurotransmitter systems
Sci Culture
Cited by (59)
Therapeutic potential of HIV nosode 30c as evaluated in A549 lung cancer cells
2017, HomeopathyCitation Excerpt :Since the nosode HIV 30c was diluted by a factor of 1060, the possibility of presence of even a single original drug molecule is extremely low, yet it showed its apparent ability to modulate the expression of well-known cancer bio-markers in a given time span, particularly noticeable in the cancer cells, though less so in the normal WRL-68 cells, while the succussed alcohol (“placebo”) without having any drug molecular imprints failed to do so in the initial control parameters tested. It seems that homeopathic potentized remedies may have the ability to trigger the “target”/“master gene(s)” and modulate precisely the action of some specific and relevant genes downstream in a “chain”, reaction, pushing them into either activation or inactivation, in a regulatory manner to restore their proper functional activities, as advocated by Khuda-Bukhsh34–40 and also supported recently by Paolo Bellavite and his colleagues.41,42 However, precise details of the mechanism by which this initial trigger is implemented needs further experimental elucidation.
Hormetic effects of extremely diluted solutions on gene expression
2015, HomeopathyCitation Excerpt :Some studies have been carried out using the microarray technique with the aim of supporting the claim that ultra-high diluted homeopathic remedies induce biological effects which thus affect the gene expression profiles. This hypothesis of Khuda-Bukhsh33,34 has been confuted by some studies of Thangapazham, Jonas et al.35,36 However this hypothesis seems to be consistent with the findings of several studies. Unfortunately these investigations used a single dilution of the homeopathic preparation and it is not possible to demonstrate the existence of hormetic effects.
Modulation of inflammation response to murine cutaneous Leishmaniosis by homeopathic medicines: Thymulin 5cH
2014, HomeopathyCitation Excerpt :More than this, a re-arrangement of gene expression is expected in immune cells stimulated by thymulin 5cH, determining an organized epigenetic regulation involving the immune system and the parasite communication. This kind of epigenetic regulation by homeopathic medicines has been observed in recent studies in vitro and in plant models.51–56 Taken as a whole the data show that thymulin 5cH treatment is able to change the dynamic of local and systemic immune reaction of mice to Leishmania (L.) amazonensis, giving rise to modified organization of both, chronic local inflammation and systemic immune cells balance.
Two Homeopathic Remedies Used Intermittently Provide Additional Protective Effects Against Hepatotoxicity Induced by Carcinogens in Mice
2012, JAMS Journal of Acupuncture and Meridian Studies
This hypothesis was presented by the author in the Invited Symposium section of the VIIIth All India Congress of Cytology and Genetics held at the University of Berhampore, Orissa, 15–18 October 1993.