Baillière's Clinical Gastroenterology
Volume 12, Issue 4, December 1998, Pages 823-841
10 Cholestasis and end-stage liver disease
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2016, CytokineCitation Excerpt :BA (biliary atresia) is the most common cause of cholestatic liver injury, which could progress to fibrosis, cirrhosis and end-stage liver disease (ESLD) [1,2]. ESLD is the consequence of cholestatic liver injury leading to irreversible liver dysfunction [3,4]. The presenting symptoms of ESLD include impaired synthesis of serum proteins and coagulation factors (quantified by INR), imbalance of glucose, lipid and protein metabolism, and impaired bile excretion [5].
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