Letter

Mefloquine-Induced Psychosis

To the Editor:

We wish to make the first report in the emergency medicine literature of acute psychosis caused by antimalarial prophylaxis. A 35-year-old air force sergeant presented to the emergency department with manic and psychotic symptoms. His symptoms had begun 1 to 2 weeks earlier and consisted of a mild decrease in sleep duration accompanied by a heightened desire to read the Bible. He experienced referential ideation, "sensing" that people were looking at him in a different way. Over the ensuing