Short communicationGeneration of myo-inositol-auxotrophic Leishmania mexicana mutants by targeted replacement of the myo-inositol-1-phosphate synthase gene☆
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Acknowledgements
I would like to thank Dorothee Harbecke and Monika Demar for excellent technical assistance and Suzanne Gokool for critically reading the manuscript.
References (18)
- et al.
1-L-myo-inositol-1-phosphate synthase
Biochim. Biophys. Acta
(1997) - et al.
Glycoconjugates in Leishmania infectivity
Biochim. Biophys. Acta
(1999) Proteophosphoglycans of Leishmania
Parasitol. Today
(2000)- et al.
Aspartate 19 and glutamate 121 are critical for transport function of the myo-inositol/H+ symporter from Leishmania donovani
J. Biol. Chem.
(1997) - et al.
Four conserved cytoplasmic sequence motifs are important for transport function of the Leishmania inositol/H(+) symporter
J. Biol. Chem.
(2000) - et al.
Phosphoglycan repeat-deficient Leishmania mexicana parasites remain infectious to macrophages and mice
J. Biol. Chem.
(2001) - et al.
Molecular cloning and characterization of a novel repeat-containing Leishmania major gene, ppg1, that encodes a membrane-associated form of proteophosphoglycan with a putative glycosylphosphatidylinositol anchor
J. Biol. Chem.
(1999) - et al.
Substrate depletion upregulates uptake of myo-inositol, glucose and adenosine in Leishmania
Mol. Biochem. Parasitol.
(1999) - et al.
Back in the water: the return of the inositol phosphates
Nat. Rev.
(2001)
There are more references available in the full text version of this article.
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Note: Nucleotide sequence data reported in this paper have been submitted to the EBI™ database with the accession numbers AJ344543 and AJ344544.
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