CommentAcute flaccid myelitis and enteroviruses: an ongoing story
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Enterovirus déjà vu
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Cited by (9)
Unmet Needs in the Evaluation, Treatment, and Recovery for 167 Children Affected by Acute Flaccid Myelitis Reported by Parents Through Social Media
2020, Pediatric NeurologyCitation Excerpt :However, larger biennial AFM clusters reported in 2014 and 2016 (326 cases were confirmed between August 2014 and June 2018), as well as in 2018 (additional 158 cases confirmed for 2018 of 311 reports under investigation), highlighted the fact that AFM rates were indeed rising.5 A number of case reports and series have been published describing mainly the 2014 and 2016 experiences with non-polio–related AFM regionally (among others, in Arizona,6 Colorado,7–9 Florida,10 Missouri,11 Utah,12 Washington,13 nationally14,15 and internationally including Argentina,16 Spain,17 Germany,18 Japan,19 China,20 and Australia/New Zealand21). These clusters of AFM coincided temporally with the first documented national outbreak of Enterovirus D68 (EV-D68),22 a respiratory virus first identified in California in 1962 but which until 2014 had remained rare.23
Infectious Myelopathies
2018, Neurologic ClinicsCitation Excerpt :EV71 and EV68 are usually isolated from stool and respiratory tract specimens, but CSF and blood specimens also should be obtained. CSF often shows pleocytosis and elevated protein.68 Treatment with IVIG, plasmapheresis, corticosteroids, and antiviral agents have shown no benefit.69
Parainfectious and Postinfectious Neurologic Syndromes
2017, Principles and Practice of Pediatric Infectious DiseasesGlobal emergence of enterovirus D68: A systematic review
2016, The Lancet Infectious DiseasesCitation Excerpt :However, past cases of acute flaccid paralysis in which enterovirus D68 was detected in cerebrospinal fluid in 2005, and a fatal case of meningomyeloencephalitis with both respiratory symptoms and acute flaccid paralysis in a previously healthy 5-year-old boy with enterovirus D68 in his cerebrospinal fluid suggest that enterovirus D68 is associated with acute flaccid paralysis.12 Furthermore, several cases of acute flaccid paralysis and cranial neuropathy have been observed in the autumn 2014 outbreak, as well as several cases with samples positive for enterovirus D68; two cases of acute flaccid paralysis in Norway, one case in France, and 25 cases of acute flaccid paralysis in Colorado and California, of which 12 tested positive for enterovirus D68.12,38,49,63–66,68 At least 107 paediatric cases of acute flaccid paralysis related to enterovirus D68 have been reported in the USA.68,79
European surveillance for enterovirus D68 during the emerging North-American outbreak in 2014
2015, Journal of Clinical Virology