Stability and structural features of the duplexes containing nucleoside analogues with a fixed N-type conformation, 2′-O,4′-C-methyleneribonucleosides
Bicyclic nucleoside analogues with a fixed N-type conformation, 2′-O,4′-C-methyleneuridine and -cytidine, were incorporated into oligonucleotides. The melting temperatures and the CD spectra of the modified DNA-DNA and modified DNA-RNA duplexes were studied.
References (15)
- et al.
Tetrahedron
(1993) - et al.
Bioorg. Med. Chem.
(1996) - et al.
Tetrahedron Lett.
(1997) - et al.
Tetrahedron
(1998) - et al.
Bioorg. Med. Chem. Lett.
(1997) - et al.
J. Mol. Biol.
(1974) - et al.
Chem. Rev.
(1990)
There are more references available in the full text version of this article.
Cited by (633)
Promising strategies employing nucleic acids as antimicrobial drugs
2024, Molecular Therapy Nucleic AcidsTargeting RNA with synthetic oligonucleotides: Clinical success invites new challenges
2024, Cell Chemical BiologyDevelopment of nucleic acid medicines based on chemical technology
2023, Advanced Drug Delivery ReviewsRecent Advances in the Development and Synthesis of Carbohydrate-Based Molecules with Promising Antibacterial Activity
2023, European Journal of Organic Chemistry
Copyright © 1998 Published by Elsevier Ltd.