Effect of a controlled high-fat versus low-fat diet on insulin sensitivity and leptin levels in African-American and Caucasian women☆
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2015, Journal of the Academy of Nutrition and DieteticsCitation Excerpt :Second, some evidence suggests that low-fat, plant-based diets can increase postprandial energy expenditure. Specifically, in a study of overweight postmenopausal women, a low-fat vegan diet followed for 14 weeks increased the thermic effect of food by 16%,36 presumably because the diet increases insulin sensitivity,37,38 which, in turn, increases the passage of glucose into cells.39 Given that plant-based diets appear to be effective for weight loss, it is noteworthy that the acceptability of vegetarian and vegan diets has been consistently found to be similar to that of other therapeutic diets.40-44
Low-fat diet with omega-3 fatty acids increases plasma insulin-like growth factor concentration in healthy postmenopausal women
2013, Nutrition ResearchCitation Excerpt :High total fat intake was positively associated with fasting insulin concentrations [19,20] and negatively associated with insulin sensitivity [21] in cross-sectional studies in nondiabetic individuals. Low-fat/high-carbohydrate diets improved insulin sensitivity [22–24] and fasting insulin concentrations [22,25,26] in several intervention studies relative to a high-fat [23,24] or habitual [22,25,26] diets in healthy individuals. We previously reported the effects of 3 test diets with varying amounts and types of dietary fat on circulating sex hormones [27] in healthy postmenopausal women.
Consumption of a high-fat diet induces central insulin resistance independent of adiposity
2011, Physiology and BehaviorCitation Excerpt :In rats, paradigms that result in insulin insensitivity also bring about resistance to the effects of leptin and the melanocortin agonist MTII. Previous studies have demonstrated that a reduction of dietary fat is able to improve peripheral insulin sensitivity in humans [59,60]. In rats, reducing dietary fat from 40% to 30% of total energy rapidly restored peripheral insulin sensitivity [34].
A perspective on vegetarian dietary patterns and risk of metabolic syndrome
2015, British Journal of Nutrition
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Supported in part by a Career Development Award from the American Diabetes Association (J.C.L.).