Hypophosphatemia and hypercalciuria in small premature infants fed human milk: Evidence for inadequate dietary phosphorus2
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Disorders of Neonatal Mineral Metabolism and Metabolic Bone Disease
2023, Principles of NeonatologyVitamin D and bone minerals in neonates
2021, Early Human DevelopmentCitation Excerpt :In healthy preterm infants, calcium absorption averages about 50% of intake both from fortified human milk and infant formula designed for preterm infants [2]. Phosphorus absorption is typically higher at about 80% or more of dietary intake [3]. Currently available enteral nutrition products when given at full volume intake are associated with a net absorption of about 100–120 mg/kg/day of calcium and 50–60 mg/kg/day of phosphorus, consistent with in utero accretion during the 3rd trimester of pregnancy [1,2].
Metabolic Bone Disease in the Neonatal Period and Its Later Sequelae
2012, Pediatric BoneMetabolic Bone Disease in the Neonatal Period and its Later Sequelae
2011, Pediatric Bone: Biology and DiseasesEndocrine Regulation of Phosphate Homeostasis
2009, Textbook of Nephro-EndocrinologyEnteral nutrition for premature infants: The role of human milk
2007, Seminars in Fetal and Neonatal MedicineCitation Excerpt :Although the measured gains were small, the effects were cumulative.40 Supplementation with both calcium and phosphorus results in normalization of biochemical indices of mineral status: serum calcium, phosphorus, and alkaline phosphatase activity, and urinary excretion of calcium and phosphorus.41,42 Mineral supplementation of unfortified human milk has been associated with improved linear growth and increased bone mineralization during and beyond the neonatal period.43
- 2
Supported by the Charles H. Hood Foundation, by Ross Laboratories, and by Research Career Development Award HD-00330 (D.W.R.).
- 1
From the Departments of Pediatrics, Laboratory Medicine, and Radiology, University of Connecticut Health Center.