Conservation surgery for recurrent carcinoma of the glottic larynx
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Cited by (40)
Early glottic cancer recurrence: A critical review on its current management
2021, Critical Reviews in Oncology/HematologyThe high stakes of head and neck surgery following radiation and chemotherapy – An assessment of complications and survival
2019, Oral OncologyCitation Excerpt :The use of upfront radiation and chemoradiation therapy for head and neck squamous cell carcinoma is rising [1–3]. However, anywhere from 5% to 40% of patients undergoing organ-preserving therapy, including all subsites, will eventually have persistent or recurrent disease [4–9]. Salvage surgery is often the best therapeutic option to control locoregional disease in this setting despite its associated high morbidity with rates reported from 17% to 71% [10–19].
Salvage Conservation Laryngeal Surgery After Radiation Therapy Failure
2015, Otolaryngologic Clinics of North AmericaCitation Excerpt :One meta-analysis review found better rates of local control in select patients without impairment of vocal fold immobility or significant extension to the subglottis or supraglottis.10 VPL as salvage surgery for early-stage glottic cancers that recur after RT has been shown to have rates of local control ranging from 55% to 100%, without significantly different functional outcomes from those who had VPL as the primary surgery.11–13 Laccourreye and colleagues14 observed a 78.1% laryngeal preservation rate for VPL in the salvage setting, strictly in patients in whom the tumor has not enlarged.
Salvage laryngectomy: Oncological and functional outcome
2011, Oral OncologyCitation Excerpt :Other authors reported higher incidences of 9–26% of paratracheal lymph node metastases,39–42 although most of these studies did not include patients with recurrent disease. Salvage surgery after radiotherapy is known to result in higher complication rates than primary surgery,11,15,19,43 with complication rates up to 77% for salvage laryngectomy9,11,13,14,16,18,19,25,43–49 and pharyngocutaneous fistula in up to 50% of the patients.9,11,13,14,18,43–46,48,49 The addition of chemotherapy to prior radiotherapy increases the complication risk of a laryngectomy: whereas overall complication rates of 28–34% and fistula rates of 12–16% are reported for laryngectomy after prior radiotherapy,9,11,13 these figures are 35–61% and 25–50% after chemoradiotherapy, respectively.11,18,49
Can I treat this small larynx lesion with radiation alone? Update on the radiation management of early (T <inf>1</inf> and T <inf>2</inf>) glottic cancer
2005, Otolaryngologic Clinics of North AmericaCitation Excerpt :Can TLE be used in the face of RT failure? Lydiatt et al [24] reported on 78 patients treated by vertical partial laryngectomy following RT failure. There was no increase in wound complications, time to decannulation, length of hospital stay, or ability to swallow.
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Current address (WML, KML): University of Nebraska Medical Center, VA Hospital and Methodist Hospital, Omaha, Nebraska.