The occurrence of N-nitroso compounds in kiwam tobacco

doi:10.1016/0304-3835(89)90134-1

Cancer Letters

Volume 46, Issue 3, August 1989, Pages 221-224

https://doi.org/10.1016/0304-3835(89)90134-1 Get rights and content

Abstract

The concentrations of tobacco-specific nitrosamines (TSNA), volatile and non-volatile N-nitroso compounds in kiwam, a fermented Indian tobacco product are presented. Total identified N-nitroso compound concentrations in kiwam ranged from 6.19 to 25.4 mg/kg fresh weight tobacco, the concentration range of TSNA was 5.43–22.2 mg/kg tobacco which accounted for 67–87% of the total identified N-nitroso compound burden. The high concentrations of TSNA found in kiwam tobacco may present a considerable exposure source to carcinogenic N-nitroso compounds for people using this type of tobacco.

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The occurrence of N-nitroso compounds in kiwam tobacco

Abstract

Fd. Chem. Toxicol.

Fd. Chem. Toxicol.

Fd. Chem. Toxicol.

Cancer Lett.

Fd. Chem. Toxicol.

Assessment of carcinogenic N-nitrosodiethanolamine in tobacco products and tobacco smoke

Carcinogenesis

Carcinogenic tobacco-specific N-nitrosamines in snuff and the saliva of snuff dippers

Cancer Res.

N-Nitrosomorpholine and other volatile N-nitrosamines in snuff tobacco

Carcinogenesis

Tobacco-specific nitrosamines, an important group of carcinogens in tobacco and tobacco smoke

Carcinogenesis

Induction of oral cavity tumours in F344 rats by tobacco-specific nitrosamines and snuff

Cancer Res.