Journal of the Autonomic Nervous System
The amplitude of synchronized cardiac sympathetic nerve activity reflects the number of activated pre- and postganglionic fibers in anesthetized cats
References (17)
Spinal cordintegration of visceral sensory systems and sympathetic nervous system reflexes
- et al.
Effect of cardiac vagal and sympathetic nerve activity on heart rate in rhythmic fluctuations
J. Auton. Nerv. Syst.
(1985) - et al.
Patterns of single unit activity in sympathetic postganglionic nerves
J. Auton. Nerv. Syst.
(1980) - et al.
Tracing of afferent and efferent pathways in the left inferior cardiac nerve of the cat using retrograde and transganglionic transport of horseradish peroxidase
Brain Res.
(1984) - et al.
Identification of the sympathetic preganglionic pathway to the cat stellate ganglion
J. Auton. Nerv. Syst.
(1984) - et al.
Spinal segmental preganglionic outflow to cervical sympathetic trunk and postganglionic cardiac sympathetic nerves
Brain Res.
(1987) - et al.
The 10-Hz rhythm in sympathetic nerve discharge
Am. J. Physiol.
(1992) Sympathetic preganglionic neurons: cytoarchitecture, ultrastructure, and biophysical properties
Cited by (85)
The impact of ageing and sex on sympathetic neurocirculatory regulation
2021, Seminars in Cell and Developmental BiologyCitation Excerpt :Considering that a critical role for burst size has emerged consistently across neurocirculatory studies [60,62,66,67], this feature likely represents an important aspect of the sympathetic signal for neurocirculatory control. Given that MSNA integrated burst size stems from the number and size of synchronously firing sympathetic APs [68], the consistent observation that burst size is linked to vasomotor adjustments suggests that sympathetic AP discharge patterns affect neurocirculatory responses. Although measuring AP discharge carries additional technical demands, sympathetic AP discharge likely represents the optimal signal for assessing neurovascular transduction in humans.
Action potential subpopulations within human muscle sympathetic nerve activity: Discharge properties and governing mechanisms
2021, Autonomic Neuroscience: Basic and ClinicalCitation Excerpt :We also speculate that the descending inputs to small and large postganglionic neurons may receive regulatory control from supramedullary regions that either avert or modify baroreflex neurocircuitry. On the basis that large APs fire predominantly in larger integrated bursts (Ninomiya et al., 1993; Salmanpour et al., 2011a; Steinback et al., 2010), differential baroreflex control of MSNA burst frequency versus size provides additional, although indirect, support for heterogeneous baroreflex regulation of AP subpopulations. For example, during LBNP, Sundlof and Wallin (Sundlöf and Wallin, 1978) found baroreflex unloading to predict the increase in burst frequency from baseline, but not the change in burst size.
Differential sympathetic response to lesion-induced chronic kidney disease in rabbits
2020, Kidney InternationalCitation Excerpt :In human studies there is no standard method for normalizing burst amplitude because the voltage depends on the placement of the electrode, and thus burst frequency is used.17 In the present study, the greater RSNA burst amplitude observed likely reflects a greater number of action potentials from activated neurons and is evidence of recruitment of previously silent fibers.19 The greater burst frequency reflects the rhythmic generation of discharges of in-phase neurons in the central nervous system, synchronized to the cardiac cycle by the baroreceptors.20
Functional selectivity of cardiac preganglionic sympathetic neurones in the rabbit heart
2018, International Journal of CardiologySympathetic transduction of cardiac sympathetic nerve activity in healthy, conscious sheep
2024, Journal of PhysiologyA century of exercise physiology: key concepts in neural control of the circulation
2024, European Journal of Applied Physiology