Cell
Volume 46, Issue 5, 29 August 1986, Pages 653-657
ArticleHydrophilic anchor-deficient Thy-1 is secreted by a class E mutant T lymphoma
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Cited by (52)
GPI anchoring of protein in yeast and mammalian cells, or: How we learned to stop worrying and love glycophospholipids
2007, Journal of Lipid ResearchCitation Excerpt :Dol-P-Man is the donor of the core mannosyl residues (Man-1, Man-2, and Man-3) of the GPI precursor (89) and is presumed also to contribute the fourth mannose residue that is essential in the yeast GPI biosynthetic pathway (Fig. 2B). Mammalian Dol-P-Man synthesis-defective mutants (termed Class E) and the temperature-sensitive yeast dpm1 mutants are blocked in GPI anchoring (77, 90, 91), as is a mammalian cell mutant with a putative defect in Dol-P-Man usage (92). GPI mannosylation can be blocked in mammalian cells by treatment with mannosamine, a compound that may act as a chain terminator (93).
Gpi1, a Saccharomyces cerevisiae protein that participates in the first step in glycosylphosphatidylinositol anchor synthesis
1996, Journal of Biological ChemistryIsolation and Characterization of Yeast Glycosylphosphatidylinositol Anchoring Mutants
1995, Methods in EnzymologyBiosynthesis and processing of the glycosylphosphatidylinositol anchor in mammalian cells
1994, Seminars in ImmunologyHow to make a glycoinositol phospholipid anchor
1992, Trends in Biochemical Sciences
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