Human macular pigment assessed by imaging fundus reflectometry
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Cited by (86)
Assessment of dietary carotenoid intake and biologic measurement of exposure in humans
2022, Methods in EnzymologyCitation Excerpt :One limitation of this method is that it requires participants to be able to physically press a button and follow verbal instructions, and therefore cannot be used in young children. MPR is an objective test quantifying the light reflected from the retina using a high-resolution spectrometer to measure macular pigment concentration (Kilbride, Alexander, Fishman, & Fishman, 1989). Participants' eyes must be dilated for a measurement via fundus reflectometry.
Photoacoustic imaging of the eye: A mini review
2016, PhotoacousticsConcordance of macular pigment measurements obtained using customized heterochromatic flicker photometry, dual-wavelength autofluorescence, and single-wavelength reflectance
2013, Experimental Eye ResearchCitation Excerpt :Therefore, AF at the macula is attenuated by MP if the excitation wavelength falls within that of the absorption spectrum of MP. Fundus reflectance, which quantitatively measures the light reflected from the retina and choroid using a reflectometer (Kilbride et al., 1989), a fundus camera (Chen et al., 2001), or a cSLO (Brindley and Willmer, 1952), has also been widely used for the measurement of MP. The reflectance method calculates MP in one of two ways; either by comparing the light reflected at the macula, some of which will be absorbed by the MP, to the light reflected at the peripheral areas, where there is minimal MP present to attenuate the reflectance; or by a spectral analysis of the reflected light (Berendschot and van Norren, 2004).
Drusen regression is associated with local changes in fundus autofluorescence in intermediate age-related macular degeneration
2013, American Journal of OphthalmologyCitation Excerpt :The criteria used for the delineation of these “background” ROIs were that at both baseline and at year-2, these areas should: (1) contain uniform levels of background FAF; (2) be located outside areas of drusen, drusen regression, and other retinal pathology; and (3) be selected in areas at the same approximate radial distance from the fovea as the relevant drusen regression ROIs for that study eye. The use of this reference accounted for individual variations in macular pigment distribution, which generally varies with distance from the fovea.25–27 The background ROIs were independently reviewed by a third grader (N.K. or W.W.) to verify conformity to these criteria.
Macular pigment: New clinical methods of detection and the role of carotenoids in age-related macular degeneration
2008, OptometryCitation Excerpt :The MPOD may be assessed indirectly by measuring the fundus reflectance in the living eye.53 Several tools such as the reflectometer,54 fundus camera attached to charge-couple device (CCD),55 and scanning laser ophthalmoscope (SLO)56 have been modified to quantify MP. The objective is to measure and compare the reflectance of the retina at a specific wavelength at the macular and peripheral regions.