Respiratory-related activity in hypoglossal neurons across sleep-waking states in cats
References (15)
- et al.
High-frequency and medium-frequency components of different inspiratory nerve discharges and their modification by various inputs
Brain Research
(1987) - et al.
Labyrinthine projection to the hypoglossal nucleus
Brain Res. Bull.
(1988) - et al.
Variations d'activités toniques, phasiques et respiratoires, au niveau bulbaire pendant l'endormement de la préparation ‘encéphale isolé’
Brain Research
(1974) - et al.
The human tongue during sleep: electromyographic activity of the genioglossus muscle
Exp. Neurol.
(1976) - et al.
A new microdrive for extracellular recording of single neurons using fine wires
Electroencephalogr. Clin. Neurophysiol.
(1984) Connectional organization of interneurons in the hypoglossal nucleus of the rat
Anat. Rec.
(1988)- et al.
Control of genioglossus muscle inspiratory activity
J. Appl. Physiol.
(1980)
Cited by (24)
Breathing during sleep
2022, Handbook of Clinical NeurologyCitation Excerpt :A suppression of the tonic and inspiratory-modulated GG activity can be observed provided that such an activity has not already reached its nadir during the preceding state of NREM sleep (Rowley et al., 1998; Katz and White, 2004; Eckert et al., 2009). While the tonic and inspiratory modulated components of GG activity are suppressed, asynchronous twitches of variable magnitude often occur scattered throughout REM sleep episodes (T in bottom trace of Fig. 7.1) (Megirian et al., 1978; Chokroverty, 1980; Richard and Harper, 1991). This twitching is analogous to that occurring during REM sleep in distal limb muscles but its intensity, pattern and timing is likely governed by distinct central sources specific for orofacial muscles.
Catecholaminergic A1/C1 neurons contribute to the maintenance of upper airway muscle tone but may not participate in NREM sleep-related depression of these muscles
2017, Respiratory Physiology and NeurobiologyCitation Excerpt :Among upper airway muscles that are innervated by hypoglossal motoneurons (XIImns) (Dobbins and Feldman, 1995; Altshuler et al., 1994; Saboisky et al., 2007; Fregosi and Ludlow, 2014), the genioglossus (GG) muscle is the most important dilator because its activation increases airway caliber (Remmers et al., 1978; Brennick et al., 2009). The activity of both XIImns and GG muscle is reduced during non-rapid eye movement (NREM) sleep and it is further suppressed during rapid eye movement (REM) sleep (Sauerland and Harper, 1976; Suratt et al., 1988; Horner et al., 1989; Richard and Harper, 1991; Mezzanotte et al., 1992; Katz and White, 2004; Saboisky et al., 2007; Eckert et al., 2009). Neural mechanisms of depression of XIImns and GG muscle activity during NREM and REM sleep have been extensively studied in different animal models, with the majority of these studies focused on mechanisms of XIImns depression during REM sleep.
Differential effect of sleep-wake states on lingual and dorsal neck muscle activity in rats
2005, Respiratory Physiology and NeurobiologySerotonergic effects on hypoglossal neural activity and reflex responses
1996, Brain ResearchThe cerebral regulation of cardiovascular and respiratory functions
1996, Seminars in Pediatric Neurology
The authors would like to thank Kestrel Kluge for editorial assistance and Dr. Robert Terreberry and Dr. Huifang Ni for their surgical assistance. This study was supported by HL22418-13.