Biochimica et Biophysica Acta (BBA) - Bioenergetics
Volume 1018, Issues 2–3, 25 July 1990, Pages 243-247
ColloquiaDifferentiation of brown adipose tissue and biogenesis of thermogenic mitochondria in situ and in cell culture
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Cited by (21)
Mitochondrial diseases and ATPase defects of nuclear origin
2004, Biochimica et Biophysica Acta - BioenergeticsCitation Excerpt :The cellular content of ATPase differs in mammalian tissues and it may vary also during ontogenetic development. Physiologically ATPase is down-regulated about 10-fold, relative to other OXPHOS complexes, in thermogenic brown fat where the electrochemical potential of proton gradient is dissipated in the form of heat by the uncoupling protein UCP1 [34]. Interestingly, the two-dimensional electrophoretic pattern of OXPHOS proteins in brown fat is almost identical with that found in patients with ATPase deficiency.
Physiological approach to maturation of brown adipocytes in primary cell culture
1997, Biochimica et Biophysica Acta - Molecular Cell ResearchDifferentiation of Brown Adipose Cells in Three-Dimensional Collagen Gel Culture
1993, Pathology Research and PracticeRegulation of UCP gene expression in brown adipocytes differentiated in primary culture. Effects of a new β-adrenoceptor agonist
1992, Molecular and Cellular Endocrinology
Copyright © 1990 Published by Elsevier B.V.