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Quantum energy levels of glutamate modulate neural biophotonic signals

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Abstract

Glutamate is the most abundant excitatory neurotransmitter in the brain, and it plays an essential and important role in neural functions. Current studies have shown that glutamate can induce neural biophotonic activity and transmission, which may involve the mechanism of photon quantum brain; however, it is unclear whether such a mechanism follows the principle of quantum mechanics. Here we show that the action of glutamate on its receptors leads to a decrease in its quantum energy levels, and glutamate then partially or completely loses its function to further induce the biophotonic activity in mouse brain slices. The reduced quantum energy levels of glutamate can be restored by direct-current electrical discharges and the use of energy transfer of chloroplast photosynthesis; hence, the quantum energy recovered glutamate can again induce significant biophotonic activity. Furthermore, the changes in quantum energy levels of glutamate are related to the exchange and transfer of electron energy on its active hydrogen atom. These findings suggest that the glutamate-induced neural biophotonic signals may be involved in the transfer of the quantum energy levels of glutamate, which implies a quantum mechanism of neurotransmitter action.

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Data availability statement

All data analysed during this study are included in this published article (and its supplementary information files). All original grey images generated by UBIS system, the processed biophoton grey images and the extracted grey values from the processed biophoton grey images in the regions of interest (ROIs) during the current study are not publicly available due to too large size (> 100 GB) but are available from the corresponding author on reasonable request.

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Acknowledgements

This work was supported by the Sci-Tech Support Plan of Hubei province (2014BEC086) and the research funds of South-Central University for Nationalities (XTZ15014, KTZ20039 and CZP 18003), and partially by the Wuhan frontier project for applied foundational research (2019020701011452), the innovation team fund of National Ethnic Affairs Commission (MZR20002), and the National Natural Science Foundation of China (31640034, 31700911).

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Author notes

  1. Zhengrong Han and Weitai Chai contributed equally to this work.

Authors and Affiliations

  1. Wuhan Institute for Neuroscience and Neuroengineering (WINN), South-Central University for Nationalities, Minzu Dadao 182, Wuhan, 430074, China

    Zhengrong Han, Weitai Chai, Zhuo Wang, Fangyan Xiao & Jiapei Dai

  2. Department of Neurobiology, College of Life Sciences, South-Central University for Nationalities, Wuhan, 430074, China

    Zhengrong Han, Weitai Chai, Zhuo Wang, Fangyan Xiao & Jiapei Dai

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  1. Zhengrong Han
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  2. Weitai Chai
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  3. Zhuo Wang
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  5. Jiapei Dai
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Contributions

JD conceived and designed the experiments; RZ, TC, and JD performed the experiments and analyzed the data; ZW, and FX provided technical support for UBIS and research materials; JD wrote the manuscript.

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Correspondence to Jiapei Dai.

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The authors declare no competing financial interests.

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Han, Z., Chai, W., Wang, Z. et al. Quantum energy levels of glutamate modulate neural biophotonic signals. Photochem Photobiol Sci 20, 343–356 (2021). https://doi.org/10.1007/s43630-021-00022-0

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