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Does an intrathecal baclofen pump impact scoliosis progression and complicate posterior spine fusion in patients with cerebral palsy?

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Abstract

Study design

Retrospective comparative study.

Objectives

In patients with cerebral palsy (CP), we determine the impact of intrathecal baclofen pumps (ITBPs) on scoliosis curve progression before posterior spine fusion (PSF) and its effects on surgical outcome.

Background

Children with CP can have rapid scoliosis progression, and high rates of surgical complications can be encountered. It is unknown whether the presence of pre-existing ITBP results in more difficult surgery and higher complication rates in similarly affected children.

Methods

This is a single-center retrospective study of CP patients undergoing PSF over a 15-year period. Demographics, comorbidities, curve magnitudes, and surgical methods were compared between patients with ITBP and those without. Postoperative complications, length of intensive care unit/hospital stay, drain use and output volume, and need for further surgery were also compared. Curve progression analysis after ITBP placement was performed on a subgroup of patients with high-quality consistent radiographs.

Results

Nineteen patients with ITBP and 49 patients without ITBP met inclusion criteria. Age, comorbidities, number of levels fused, and fixation techniques during PSF were not significantly different between cohorts. ITBP patients were more likely to have PSF with osteotomy (p = 0.022). Increased intraoperative neurosurgical consultations were found for patients with ITBP (42.1% vs. 4.0%; p < 0.001). Median surgical time was 1.2 h greater in patients with ITBP (6.7 vs. 5.5 h, p = 0.039). There was no difference in hospital course and complications in patients with ITBP and those without ITBP. Thirty-one patients without ITB were compared with 15 ITBP patients for curve progression before PSF, demonstrating a mean rate of scoliosis progression of 9.6° ± 6.7°/year and 14.8° ± 9.1°/year (p = 0.0346), respectively.

Conclusion

The presence of an ITBP appears to be associated with the increase in scoliosis progression; and these patients will likely have a more challenging spine fusion. Fortunately, the final outcome is not affected by ITBP.

Level of evidence

Level III.

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Funding

Shapiro Summer Research; UW Department of Orthopedics and Rehabilitation.

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Authors and Affiliations

  1. Department of Orthopedics and Rehabilitation, University of Wisconsin School of Medicine and Public Health, 750 Highland Ave, Madison, WI, 53726, USA

    Laura A. B. Lins, Anatoliy V. Nechyporenko, Matthew A. Halanski, Scott J. Hetzel & Kenneth J. Noonan

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  1. Laura A. B. Lins
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  2. Anatoliy V. Nechyporenko
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  3. Matthew A. Halanski
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  4. Scott J. Hetzel
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  5. Kenneth J. Noonan
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Corresponding author

Correspondence to Laura A. B. Lins.

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Conflict of interest

LABL (none), AVN (none), MAH (none), SJH (none), KJN (a patent “Spine Implants” with royalties paid to Biomet).

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Approval was obtained from the University of Wisconsin institutional review board.

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Lins, L.A.B., Nechyporenko, A.V., Halanski, M.A. et al. Does an intrathecal baclofen pump impact scoliosis progression and complicate posterior spine fusion in patients with cerebral palsy?. Spine Deform 8, 115–121 (2020). https://doi.org/10.1007/s43390-020-00034-3

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  • DOI: https://doi.org/10.1007/s43390-020-00034-3

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