Abstract
To determine the prevalence of restless legs syndrome (RLS) among Japanese pregnant women without complications and to clarify the correlation between RLS and clinical outcomes, RLS screening was conducted using the Johns Hopkins Telephone Diagnostic Interview for 140 pregnant women in their third trimester. The frequency of positive RLS screening test was 15.7%. No significant differences were found in the hemoglobin, ferritin, and folate levels and in the delivery outcomes between the RLS and control groups. In the future, it will be necessary to clarify whether a similarly high prevalence of RLS exists in Japanese pregnant women with complications.
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References
Picchietti DL, Hensley JG, Bainbridge JL, Lee KA, Manconi M, McGregor JA, Silver RM, Trenkwalder C, Walters AS. Consensus clinical practice guidelines for the diagnosis and treatment of restless legs syndrome/Willis-Ekbom disease during pregnancy and lactation. Sleep Med Rev. 2015;22:64–77.
Ma S, Shang X, Guo Y, Liu G, Yang J, Xue R. Restless legs syndrome and hypertension in Chinese pregnant women. Neurol Sci. 2015;36:877–81.
Harano S, Ohida T, Kaneita Y, Yokoyama E, Tamaki T, Takemura S, Osaki Y, Hayashi K. Prevalence of restless legs syndrome with pregnancy and the relationship with sleep disorders in the Japanese large population. Sleep Biol Rhythms. 2008;6:102–9.
Suzuki K, Ohida T, Sone T, Takemura S, Yokoyama E, Miyake T, Harano S, Motojima S, Suga M, Ibuka E. The prevalence of restless legs syndrome among pregnant women in Japan and the relationship between restless legs syndrome and sleep problems. Sleep. 2003;26:673–7.
Alves DA, Carvalho LB, Morais JF, Prado GF. Restless legs syndrome during pregnancy in Brazilian women. Sleep Med. 2010;11:1049–54.
Bourguet CC, Ober SK, Panzner MP, Baughman KR. Evaluation of a screening interview for restless legs syndrome. Acta Neurol Scand. 2009;120:24–9.
Kobayashi M, Kato K, Kagimura T, Inoue Y. Evaluation of reliability and validity of Japanese IRLS ver2.2 in severity evaluation of restless legs syndrome (RLS). Japn J Sleep Med. 2013;7:100–5.
Cesnik E, Casetta I, Turri M, Govoni V, Granieri E, Strambi LF, Manconi M. Transient RLS during pregnancy is a risk factor for the chronic idiopathic form. Neurology. 2010;75:2117–20.
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This work was supported by JSPS KAKENHI Grant Number JP25670973.
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All authors declare that they have no conflict of interest.
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This study was approved by the Ethics Committee of Nagasaki University Graduate School of Biomedical Sciences (Approval No. 13032889).
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Hatanaka, A., Eto, H., Kato, C. et al. Prevalence and clinical features of restless legs syndrome among Japanese pregnant women without gestational complications. Sleep Biol. Rhythms 15, 183–186 (2017). https://doi.org/10.1007/s41105-016-0086-2
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DOI: https://doi.org/10.1007/s41105-016-0086-2