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Papillary thyroid carcinoma and multiple endocrine neoplasia type 2

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Abstract

Introduction

Papillary thyroid carcinoma (PTC) is exceptional in MEN 2.

Results

The analysis in 135 patients revealed two PTC, without C-cell pathology; both being positive for V804M mutation (RET proto-oncogene).

Conclusions

Few data are available about PTC in MEN 2, and without C-cell pathology is even less common. More studies are needed to correlate genetics and histology, and even for assessing PTC as only manifestation of MEN 2.

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Conflict of interest

The authors declare that they have no conflict of interest.

Research involving human participants

For this type of study, formal consent is not required.

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Informed consent was obtained from all individual participants included in the study.

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Authors and Affiliations

  1. Service of General Surgery, Unit of Endocrine Surgery, Instituto Murciano de Investigaciones Biomédicas (IMIB), Virgen de la Arrixaca Clinical Universitary Hospital, Crta./Madrid-Cartagena, s/n. El Palmar, 30120, Murcia, Spain

    B. Febrero, J. M. Rodríguez, A. Ríos & P. Parrilla

  2. Service of Endocrinology, Virgen de la Arrixaca Clinical Universitary Hospital, Crta./Madrid-Cartagena, s/n. El Palmar, 30120, Murcia, Spain

    P. Portillo

Authors
  1. B. Febrero
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  2. J. M. Rodríguez
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  3. A. Ríos
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  4. P. Portillo
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  5. P. Parrilla
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Corresponding author

Correspondence to B. Febrero.

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Febrero, B., Rodríguez, J.M., Ríos, A. et al. Papillary thyroid carcinoma and multiple endocrine neoplasia type 2. J Endocrinol Invest 38, 1233–1237 (2015). https://doi.org/10.1007/s40618-015-0290-y

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  • DOI: https://doi.org/10.1007/s40618-015-0290-y

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